α-Synuclein Translocates to the Nucleus to Activate Retinoic-Acid-Dependent Gene Transcription

α-Synuclein (α-Syn) protein is implicated in the pathogenesis of Parkinson disease (PD). It is primarily cytosolic and interacts with cell membranes. α-Syn also occurs in the nucleus. Here we investigated the mechanisms involved in nuclear translocation of α-Syn. We analyzed alterations in gene expr...

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Detalles Bibliográficos
Autores principales: Davidi, Dana, Schechter, Meir, Elhadi, Suaad Abd, Matatov, Adar, Nathanson, Lubov, Sharon, Ronit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052517/
https://www.ncbi.nlm.nih.gov/pubmed/32120069
http://dx.doi.org/10.1016/j.isci.2020.100910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052517/
https://www.ncbi.nlm.nih.gov/pubmed/32120069
http://dx.doi.org/10.1016/j.isci.2020.100910

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