Towards next generation therapies for cystic fibrosis: Folding, function and pharmacology of CFTR()

The treatment of cystic fibrosis (CF) has been transformed by orally-bioavailable small molecule modulators of the cystic fibrosis transmembrane conductance regulator (CFTR), which restore function to CF mutants. However, CFTR modulators are not available to all people with CF and better modulators...

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Detalles Bibliográficos
Autores principales: Bose, Samuel J., Krainer, Georg, Ng, Demi R.S., Schenkel, Mathias, Shishido, Hideki, Yoon, Jae Seok, Haggie, Peter M., Schlierf, Michael, Sheppard, David N., Skach, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052731/
https://www.ncbi.nlm.nih.gov/pubmed/31902693
http://dx.doi.org/10.1016/j.jcf.2019.12.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052731/
https://www.ncbi.nlm.nih.gov/pubmed/31902693
http://dx.doi.org/10.1016/j.jcf.2019.12.009

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