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Histamine‐induced plasticity and gene expression in corticostriatal pathway under hyperammonemia

AIMS: Histamine H3 receptor (H3R) antagonists/inverse agonists increase vigilance. We studied brain histaminergic pathways under hyperammonemia and the transcriptome of receptors and their signaling cascades to provide a rationale for wake‐promoting therapies. METHODS: We analyzed histamine‐induced...

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Detalles Bibliográficos
Autores principales: Sergeeva, Olga A., Chepkova, Aisa N., Görg, Boris, Rodrigues Almeida, Filipe, Bidmon, Hans‐Jürgen, Haas, Helmut L., Häussinger, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052803/
https://www.ncbi.nlm.nih.gov/pubmed/31571389
http://dx.doi.org/10.1111/cns.13223