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Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: Boosting the efficacy of intravenously administered therapeutic adenoviruses

Oncolytic adenoviruses are used as agents for the treatment of cancer. However, their potential is limited due to the high seroprevalence of anti-adenovirus neutralizing antibodies (nAbs) within the population and the rapid liver sequestration when systemically administered. To overcome these challe...

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Detalles Bibliográficos
Autores principales: Brugada-Vilà, Pau, Cascante, Anna, Lázaro, Miguel Ángel, Castells-Sala, Cristina, Fornaguera, Cristina, Rovira-Rigau, Maria, Albertazzi, Lorenzo, Borros, Salvador, Fillat, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052890/
https://www.ncbi.nlm.nih.gov/pubmed/32194832
http://dx.doi.org/10.7150/thno.40902