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Apigenin and Abivertinib, a novel BTK inhibitor synergize to inhibit diffuse large B-cell lymphoma in vivo and vitro

Background: Apigenin, a flavonoid phytochemical extracted from fruits and vegetables, has shown anti-neoplastic effects in a variety of malignant tumors. DLBCL is the most common type of aggressive lymphoma in adults with a poor prognosis. Small-molecule inhibitors like BTK inhibitors have demonstra...

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Detalles Bibliográficos
Autores principales: Huang, Shujuan, Yu, Mengxia, Shi, Nana, Zhou, Yile, Li, Fengling, Li, Xia, Huang, Xin, Jin, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052937/
https://www.ncbi.nlm.nih.gov/pubmed/32127939
http://dx.doi.org/10.7150/jca.34981