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Macrovascular Endothelial Cells Enhance the Motility of Liver Cancer Cells by Up-regulation of MMP-3, Activation of Integrin/FAK Signaling Pathway and Induction of Non-classical Epithelial-mesenchymal Transition

Background: Liver cancer with portal vein tumor thrombus (PVTT) indicates a serious prognosis. The molecular mechanism of PVTT formation is not totally clarified, the invasion of blood vessels by liver cancer cells is the key step and portal vein endothelial cells plays critical role. Methods: Condi...

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Detalles Bibliográficos
Autores principales: Ding, Song-Ming, Lu, Ai-Li, Lu, Jian-Fang, Chen, Xu-Liang, Edoo, Muhammad Ibrahim Alhadi, Zhou, Lin, Xie, Hai-Yang, Zheng, Shu-Sen, Li, Qi-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052939/
https://www.ncbi.nlm.nih.gov/pubmed/32127932
http://dx.doi.org/10.7150/jca.38209