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Intra-articular delivery of extracellular vesicles secreted by chondrogenic progenitor cells from MRL/MpJ superhealer mice enhances articular cartilage repair in a mouse injury model

BACKGROUND: Chondrogenic progenitor cells (CPCs) have high self-renewal capacity and chondrogenic potential. Intra-articular delivery of purified mesenchymal stem cells (MSCs) from MRL/MpJ “superhealer” mice increased bone volume during repair and prevents post-traumatic arthritis. Recently, althoug...

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Detalles Bibliográficos
Autores principales: Wang, Rikang, Jiang, Wei, Zhang, Lang, Xie, Saisai, Zhang, Shuai, Yuan, Shun, Jin, Yi, Zhou, Guangqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052980/
https://www.ncbi.nlm.nih.gov/pubmed/32122385
http://dx.doi.org/10.1186/s13287-020-01594-x