Cargando…

New uracil analog U-332 is an inhibitor of NF-κB in 5-fluorouracil-resistant human leukemia HL-60 cell line

BACKGROUND: 5-Fluorouracil (5-FU) is an antimetabolite that interferes with DNA synthesis and has been widely used as a chemotherapeutic drug in various types of cancers. However, the development of drug resistance greatly limits its application. Overexpression of ATP-binding cassette (ABC) transpor...

Descripción completa

Detalles Bibliográficos
Autores principales: Długosz-Pokorska, Angelika, Pięta, Marlena, Kędzia, Jacek, Janecki, Tomasz, Janecka, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053076/
https://www.ncbi.nlm.nih.gov/pubmed/32122395
http://dx.doi.org/10.1186/s40360-020-0397-4