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Contaminant DNA in bacterial sequencing experiments is a major source of false genetic variability

BACKGROUND: Contaminant DNA is a well-known confounding factor in molecular biology and in genomic repositories. Strikingly, analysis workflows for whole-genome sequencing (WGS) data commonly do not account for errors potentially introduced by contamination, which could lead to the wrong assessment...

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Detalles Bibliográficos
Autores principales: Goig, Galo A., Blanco, Silvia, Garcia-Basteiro, Alberto L., Comas, Iñaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053099/
https://www.ncbi.nlm.nih.gov/pubmed/32122347
http://dx.doi.org/10.1186/s12915-020-0748-z