LK-DFBA: a linear programming-based modeling strategy for capturing dynamics and metabolite-dependent regulation in metabolism

BACKGROUND: The systems-scale analysis of cellular metabolites, “metabolomics,” provides data ideal for applications in metabolic engineering. However, many of the computational tools for strain design are built around Flux Balance Analysis (FBA), which makes assumptions that preclude direct integra...

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Detalles Bibliográficos
Autores principales: Dromms, Robert A., Lee, Justin Y., Styczynski, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053146/
https://www.ncbi.nlm.nih.gov/pubmed/32122331
http://dx.doi.org/10.1186/s12859-020-3422-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053146/
https://www.ncbi.nlm.nih.gov/pubmed/32122331
http://dx.doi.org/10.1186/s12859-020-3422-0

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