PI3K/AKT inhibition reverses R-CHOP resistance by destabilizing SOX2 in diffuse large B cell lymphoma

Up to one-third of diffuse large B cell lymphoma (DLBCL) patients eventually develop resistance to R-CHOP regimen, while the remaining therapeutic options are limited. Thus, understanding the underlying mechanisms and developing therapeutic approaches are urgently needed. Methods: We generated two g...

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Detalles Bibliográficos
Autores principales: Chen, Jianfeng, Ge, Xiaowen, Zhang, Wei, Ding, Peipei, Du, Yiqun, Wang, Qi, Li, Ling, Fang, Lan, Sun, Yujing, Zhang, Pingzhao, Zhou, Yuzhen, Zhang, Long, Lv, Xinyue, Li, Luying, Zhang, Xin, Zhang, Qunling, Xue, Kai, Gu, Hongyu, Lei, Qunying, Wong, Jiemin, Hu, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053184/
https://www.ncbi.nlm.nih.gov/pubmed/32194860
http://dx.doi.org/10.7150/thno.41362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053184/
https://www.ncbi.nlm.nih.gov/pubmed/32194860
http://dx.doi.org/10.7150/thno.41362

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