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Focused ultrasound as a novel strategy for noninvasive gene delivery to retinal Müller glia

Müller glia are specialized retinal cells with stem cell properties in fish and frogs but not in mammals. Current efforts to develop gene therapies to activate mammalian Müller glia for retinal repair will require safe and effective delivery strategies for recombinant adeno-associated viruses (AAVs)...

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Detalles Bibliográficos
Autores principales: Touahri, Yacine, Dixit, Rajiv, Kofoed, Rikke Hahn, Mikloska, Kristina, Park, EunJee, Raeisossadati, Reza, Markham-Coultes, Kelly, David, Luke Ajay, Rijal, Hibo, Zhao, Jiayi, Lynch, Madelaine, Hynynen, Kullervo, Aubert, Isabelle, Schuurmans, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053200/
https://www.ncbi.nlm.nih.gov/pubmed/32194850
http://dx.doi.org/10.7150/thno.42611