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Combined elevation of TRIB2 and MAP3K1 indicates poor prognosis and chemoresistance to temozolomide in glioblastoma

INTRODUCTION: Glioblastoma (GBM) is the most lethal primary malignant brain tumor in adults with poor survival due to acquired therapeutic resistance and rapid recurrence. Currently, the standard clinical strategy for glioma includes maximum surgical resection, radiotherapy, and temozolomide (TMZ) c...

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Detalles Bibliográficos
Autores principales: Wang, Jia, Zuo, Jie, Wahafu, Alafate, Wang, Mao‐de, Li, Rui‐chun, Xie, Wan‐fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053231/
https://www.ncbi.nlm.nih.gov/pubmed/31318172
http://dx.doi.org/10.1111/cns.13197