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The potential of combined mutation sequencing of plasma circulating cell‐free DNA and matched white blood cells for treatment response prediction

Highly sensitive mutation detection methods enable the application of circulating cell‐free DNA for molecular tumor profiling. Recent studies revealed that sequencing artifacts, germline variants, and clonal hematopoiesis confound the interpretation of sequencing results and complicate subsequent tr...

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Detalles Bibliográficos
Autores principales: van der Leest, Paul, Schuuring, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053232/
https://www.ncbi.nlm.nih.gov/pubmed/32017376
http://dx.doi.org/10.1002/1878-0261.12646