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Development of a RP-HPLC method for analysis of docetaxel in tumor-bearing mice plasma and tissues following injection of docetaxel-loaded pH responsive targeting polymeric micelles

BACKGROUND AND PURPOSE: A simple, rapid, and sensitive reversed-phase high performance liquid chromatography (RP-HPLC) method based on liquid-liquid extraction was developed and validated for determination of docetaxel (DTX) in plasma and homogenate tissues of tumor-bearing mice. EXPERIMENTAL APPROA...

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Detalles Bibliográficos
Autores principales: Kazemi, Moloud, Emami, Jaber, Hasanzadeh, Farshid, Minaiyan, Mohsen, Mirian, Mina, Lavasanifar, Afsaneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053291/
https://www.ncbi.nlm.nih.gov/pubmed/32180812
http://dx.doi.org/10.4103/1735-5362.278710