The CARM1-p300-c-Myc-Max (CPCM) transcriptional complex regulates the expression of CUL4A/4B and affects the stability of CRL4 E3 ligases in colorectal cancer

The transcription factor c-Myc and two cullin family members CUL4A/4B function as oncogenes in colorectal cancer. Our recent publication reveals that c-Myc specifically activates the expression of CUL4A/4B through binding to their promoters. However, the underlying mechanism of how c-Myc actions in...

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Detalles Bibliográficos
Autores principales: Lu, Wenzhu, Yang, Chunmei, He, Hongbo, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053342/
https://www.ncbi.nlm.nih.gov/pubmed/32140074
http://dx.doi.org/10.7150/ijbs.41230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053342/
https://www.ncbi.nlm.nih.gov/pubmed/32140074
http://dx.doi.org/10.7150/ijbs.41230

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