Drug-drug interaction of acetaminophen and roxithromycin with the cocktail of cytochrome P450 and hepatotoxicity in rats

Acetaminophen (APAP) and roxithromycin (ROX) are often used in combination in clinical practice. To evaluate their drug-drug interactions (DDIs) and the hepatotoxicity of co-administration, rats were randomly separated into four groups: Control, APAP (50 mg/kg), ROX (5.5 mg/kg) and APAP-ROX (50 mg/k...

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Detalles Bibliográficos
Autores principales: Liu, Xiang, Chen, Chen, Zhang, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053348/
https://www.ncbi.nlm.nih.gov/pubmed/32132876
http://dx.doi.org/10.7150/ijms.38527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053348/
https://www.ncbi.nlm.nih.gov/pubmed/32132876
http://dx.doi.org/10.7150/ijms.38527

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