Cargando…

Hinokitiol reduces tumor metastasis by inhibiting heparanase via extracellular signal-regulated kinase and protein kinase B pathway

Heparanase cleaves the extracellular matrix by degrading heparan sulfate that ultimately leads to cell invasion and metastasis; a condition that causes high mortality among cancer patients. Many of the anticancer drugs available today are natural products of plant origin, such as hinokitiol. In the...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Yueh-Jung, Hsu, Wei-Jie, Wu, Li-Hsien, Liou, Huei-Pu, Pangilinan, Christian Ronquillo, Tyan, Yu-Chang, Lee, Che-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053356/
https://www.ncbi.nlm.nih.gov/pubmed/32132875
http://dx.doi.org/10.7150/ijms.41177