Hinokitiol reduces tumor metastasis by inhibiting heparanase via extracellular signal-regulated kinase and protein kinase B pathway

Heparanase cleaves the extracellular matrix by degrading heparan sulfate that ultimately leads to cell invasion and metastasis; a condition that causes high mortality among cancer patients. Many of the anticancer drugs available today are natural products of plant origin, such as hinokitiol. In the...

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Detalles Bibliográficos
Autores principales: Wu, Yueh-Jung, Hsu, Wei-Jie, Wu, Li-Hsien, Liou, Huei-Pu, Pangilinan, Christian Ronquillo, Tyan, Yu-Chang, Lee, Che-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053356/
https://www.ncbi.nlm.nih.gov/pubmed/32132875
http://dx.doi.org/10.7150/ijms.41177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053356/
https://www.ncbi.nlm.nih.gov/pubmed/32132875
http://dx.doi.org/10.7150/ijms.41177

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