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Propofol Causes Consciousness Loss by Affecting GABA-A Receptor in the Nucleus Basalis of Rats

OBJECTIVE: Propofol is a classical anesthetic and induces consciousness loss, and gamma-aminobutyric-acid-type-A (GABA-A) receptor is its target. Righting reflex is associated with conscious response. The nucleus basalis (NB) acts as a major relay between the reticular activating system and the fron...

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Detalles Bibliográficos
Autores principales: Xing, Yunlong, Li, Kai, Jiao, Yuan, Li, Zinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053451/
https://www.ncbi.nlm.nih.gov/pubmed/32148565
http://dx.doi.org/10.1155/2020/9370891