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Impaired Airway Epithelial Barrier Integrity in Response to Stenotrophomonas maltophilia Proteases, Novel Insights Using Cystic Fibrosis Bronchial Epithelial Cell Secretomics

Stenotrophomonas maltophilia is a Gram-negative opportunistic pathogen that can chronically colonize the lungs of people with cystic fibrosis (CF) and is associated with lethal pulmonary hemorrhage in immunocompromised patients. Its secreted virulence factors include the extracellular serine proteas...

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Detalles Bibliográficos
Autores principales: Molloy, Kevin, Cagney, Gerard, Dillon, Eugene T., Wynne, Kieran, Greene, Catherine M., McElvaney, Noel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053507/
https://www.ncbi.nlm.nih.gov/pubmed/32161586
http://dx.doi.org/10.3389/fimmu.2020.00198