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K63 ubiquitin chains target NLRP3 inflammasome for autophagic degradation in ox-LDL-stimulated THP-1 macrophages

Inflammation, especially involving the NLRP3 inflammasome, is critical to atherosclerotic plaque formation. Enhanced autophagy can inhibit the development of atherosclerosis, and recent studies have revealed that NLRP3 inflammasome can be degraded by autophagy in atherosclerosis. In the present stud...

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Detalles Bibliográficos
Autores principales: Zhou, Zhenfeng, Zhu, Xiaoyan, Yin, Ruihua, Liu, Tianwei, Yang, Shaonan, Zhou, Lingyan, Pan, Xudong, Ma, Aijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053591/
https://www.ncbi.nlm.nih.gov/pubmed/32003754
http://dx.doi.org/10.18632/aging.102710