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K63 ubiquitin chains target NLRP3 inflammasome for autophagic degradation in ox-LDL-stimulated THP-1 macrophages
Inflammation, especially involving the NLRP3 inflammasome, is critical to atherosclerotic plaque formation. Enhanced autophagy can inhibit the development of atherosclerosis, and recent studies have revealed that NLRP3 inflammasome can be degraded by autophagy in atherosclerosis. In the present stud...
Autores principales: | Zhou, Zhenfeng, Zhu, Xiaoyan, Yin, Ruihua, Liu, Tianwei, Yang, Shaonan, Zhou, Lingyan, Pan, Xudong, Ma, Aijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053591/ https://www.ncbi.nlm.nih.gov/pubmed/32003754 http://dx.doi.org/10.18632/aging.102710 |
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