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Chitosan-Coated PLGA Nanoparticles for Enhanced Ocular Anti-Inflammatory Efficacy of Atorvastatin Calcium

BACKGROUND: Atorvastatin calcium (AT) is an ocular anti-inflammatory with limited bioavailability when taken orally due to its low solubility in low pH and extensive first-pass effect. To overcome these problems, AT was entrapped in polymeric nanoparticles (NPs) to improve surface properties and sus...

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Detalles Bibliográficos
Autores principales: Arafa, Mona G, Girgis, Germeen N S, El-Dahan, Marwa S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053815/
https://www.ncbi.nlm.nih.gov/pubmed/32184589
http://dx.doi.org/10.2147/IJN.S237314