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Aberrant expression of the UPF1 RNA surveillance gene disturbs keratinocyte homeostasis by stabilizing AREG

The up-frameshift suppressor 1 homolog (UPF1) RNA surveillance gene is a core element in the nonsense-mediated RNA decay (NMD) pathway, which impacts a broad spectrum of biological processes in a cell-specific manner. In the present study, the contribution of the NMD pathway to psoriasis lesions and...

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Detalles Bibliográficos
Autores principales: Cheng, Yaojia, Lu, Qiuping, Shi, Nannan, Zhou, Qiongyan, Rong, Jingjing, Li, Liyun, Wang, Li, Liu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053862/
https://www.ncbi.nlm.nih.gov/pubmed/32124941
http://dx.doi.org/10.3892/ijmm.2020.4487