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Chromomycin A3 suppresses cholangiocarcinoma growth by induction of S phase cell cycle arrest and suppression of Sp1-related anti-apoptotic proteins

Cholangiocarcinoma (CCA) is a cancer of biliary epithelium. Late diagnosis and resistance to conventional chemotherapy are the major obstacles in CCA treatment. Increased expression of anti-apoptotic proteins are observed in CCA, which might confer chemoresistance. Thus, modulations of anti-apoptoti...

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Detalles Bibliográficos
Autores principales: Saranaruk, Paksiree, Kariya, Ryusho, Sittithumcharee, Gunya, Boueroy, Parichart, Boonmars, Thidarut, Sawanyawisuth, Kanlayanee, Wongkham, Chaisiri, Wongkham, Sopit, Okada, Seiji, Vaeteewoottacharn, Kulthida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053871/
https://www.ncbi.nlm.nih.gov/pubmed/32124934
http://dx.doi.org/10.3892/ijmm.2020.4482