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Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta

Despite the medical importance of G protein-coupled receptors (GPCRs), in vivo cellular heterogeneity of GPCR signaling and downstream transcriptional responses are not understood. We report the comprehensive characterization of transcriptomes (bulk and single-cell) and chromatin domains regulated b...

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Detalles Bibliográficos
Autores principales: Engelbrecht, Eric, Levesque, Michel V, He, Liqun, Vanlandewijck, Michael, Nitzsche, Anja, Niazi, Hira, Kuo, Andrew, Singh, Sasha A, Aikawa, Masanori, Holton, Kristina, Proia, Richard L, Kono, Mari, Pu, William T, Camerer, Eric, Betsholtz, Christer, Hla, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054001/
https://www.ncbi.nlm.nih.gov/pubmed/32091396
http://dx.doi.org/10.7554/eLife.52690