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Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta
Despite the medical importance of G protein-coupled receptors (GPCRs), in vivo cellular heterogeneity of GPCR signaling and downstream transcriptional responses are not understood. We report the comprehensive characterization of transcriptomes (bulk and single-cell) and chromatin domains regulated b...
Autores principales: | Engelbrecht, Eric, Levesque, Michel V, He, Liqun, Vanlandewijck, Michael, Nitzsche, Anja, Niazi, Hira, Kuo, Andrew, Singh, Sasha A, Aikawa, Masanori, Holton, Kristina, Proia, Richard L, Kono, Mari, Pu, William T, Camerer, Eric, Betsholtz, Christer, Hla, Timothy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054001/ https://www.ncbi.nlm.nih.gov/pubmed/32091396 http://dx.doi.org/10.7554/eLife.52690 |
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