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Impact of Chromosome Fusions on 3D Genome Organization and Gene Expression in Budding Yeast

The three-dimensional (3D) organization of chromosomes can influence transcription. However, the frequency and magnitude of these effects remain debated. To determine how changes in chromosome positioning affect transcription across thousands of genes with minimal perturbation, we characterized nucl...

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Detalles Bibliográficos
Autores principales: Di Stefano, Marco, Di Giovanni, Francesca, Pozharskaia, Vasilisa, Gomar-Alba, Mercè, Baù, Davide, Carey, Lucas B., Marti-Renom, Marc A., Mendoza, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054015/
https://www.ncbi.nlm.nih.gov/pubmed/31907200
http://dx.doi.org/10.1534/genetics.119.302978