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Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice

Neural stem cells in the lateral ganglionic eminence (LGE) generate progenitors that migrate through the rostral migratory stream (RMS) to repopulate olfactory bulb (OB) interneurons, but the regulation of this process is poorly defined. The evolutionarily conserved Notch pathway is essential for ne...

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Detalles Bibliográficos
Autores principales: Blackwood, Christopher A., Bailetti, Alessandro, Nandi, Sayan, Gridley, Thomas, Hébert, Jean M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054221/
https://www.ncbi.nlm.nih.gov/pubmed/32161758
http://dx.doi.org/10.3389/fcell.2020.00113