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Modification of an Anopheles gambiae odorant binding protein to create an array of chemical sensors for detection of drugs

The binding pockets of odorant binding proteins from Anopheles gambiae (OBP1 and OBP47) were analysed using in silico modelling. The feasibility of creating mutant proteins to achieve a protein array capable of detecting drugs of abuse in solution or in vapour phase was investigated. OBP1 was found...

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Detalles Bibliográficos
Autores principales: Cali, Khasim, Persaud, Krishna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054253/
https://www.ncbi.nlm.nih.gov/pubmed/32127578
http://dx.doi.org/10.1038/s41598-020-60824-7