Novel roles of PRK1 and PRK2 in cilia and cancer biology

PRK1 and PRK2 are two closely related AGC-family serine/threonine protein kinases. Here we demonstrate novel roles for them at cilia and in cancer biology. In both instances serum withdrawal leads to increased activating PRK1 and PRK2 phosphorylation (pPRK1/pPRK2) and their depletion results in redu...

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Detalles Bibliográficos
Autores principales: Patel, Hitesh, Li, Jun, Herrero, Ana, Kroboth, Jakob, Byron, Adam, Kriegsheim, Alex Von, Brunton, Valerie, Carragher, Neil, Hurd, Toby, Frame, Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054267/
https://www.ncbi.nlm.nih.gov/pubmed/32127582
http://dx.doi.org/10.1038/s41598-020-60604-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054267/
https://www.ncbi.nlm.nih.gov/pubmed/32127582
http://dx.doi.org/10.1038/s41598-020-60604-3

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