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Novel roles of PRK1 and PRK2 in cilia and cancer biology
PRK1 and PRK2 are two closely related AGC-family serine/threonine protein kinases. Here we demonstrate novel roles for them at cilia and in cancer biology. In both instances serum withdrawal leads to increased activating PRK1 and PRK2 phosphorylation (pPRK1/pPRK2) and their depletion results in redu...
Autores principales: | Patel, Hitesh, Li, Jun, Herrero, Ana, Kroboth, Jakob, Byron, Adam, Kriegsheim, Alex Von, Brunton, Valerie, Carragher, Neil, Hurd, Toby, Frame, Margaret |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054267/ https://www.ncbi.nlm.nih.gov/pubmed/32127582 http://dx.doi.org/10.1038/s41598-020-60604-3 |
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