Cargando…
Development of genetic quality tests for good manufacturing practice-compliant induced pluripotent stem cells and their derivatives
Although human induced pluripotent stem cell (hiPSC) lines are karyotypically normal, they retain the potential for mutation in the genome. Accordingly, intensive and relevant quality controls for clinical-grade hiPSCs remain imperative. As a conceptual approach, we performed RNA-seq-based broad-ran...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054319/ https://www.ncbi.nlm.nih.gov/pubmed/32127560 http://dx.doi.org/10.1038/s41598-020-60466-9 |