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Development of genetic quality tests for good manufacturing practice-compliant induced pluripotent stem cells and their derivatives

Although human induced pluripotent stem cell (hiPSC) lines are karyotypically normal, they retain the potential for mutation in the genome. Accordingly, intensive and relevant quality controls for clinical-grade hiPSCs remain imperative. As a conceptual approach, we performed RNA-seq-based broad-ran...

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Detalles Bibliográficos
Autores principales:	Jo, Hye-Yeong, Han, Hyo-Won, Jung, Inuk, Ju, Ji Hyeon, Park, Soon-Jung, Moon, Sunghwan, Geum, Dongho, Kim, Hyemin, Park, Han-Jin, Kim, Sun, Stacey, Glyn N., Koo, Soo Kyung, Park, Mi-Hyun, Kim, Jung-Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054319/ https://www.ncbi.nlm.nih.gov/pubmed/32127560 http://dx.doi.org/10.1038/s41598-020-60466-9

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