Refined spatial temporal epigenomic profiling reveals intrinsic connection between PRDM9-mediated H3K4me3 and the fate of double-stranded breaks

Meiotic recombination is initiated by the formation of double-strand breaks (DSBs), which are repaired as either crossovers (COs) or noncrossovers (NCOs). In most mammals, PRDM9-mediated H3K4me3 controls the nonrandom distribution of DSBs; however, both the timing and mechanism of DSB fate control r...

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Detalles Bibliográficos
Autores principales: Chen, Yao, Lyu, Ruitu, Rong, Bowen, Zheng, Yuxuan, Lin, Zhen, Dai, Ruofei, Zhang, Xi, Xie, Nannan, Wang, Siqing, Tang, Fuchou, Lan, Fei, Tong, Ming-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054334/
https://www.ncbi.nlm.nih.gov/pubmed/32047271
http://dx.doi.org/10.1038/s41422-020-0281-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054334/
https://www.ncbi.nlm.nih.gov/pubmed/32047271
http://dx.doi.org/10.1038/s41422-020-0281-1

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