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Hyper BOLD Activation in Dorsal Raphe Nucleus of APP/PS1 Alzheimer’s Disease Mouse during Reward-Oriented Drinking Test under Thirsty Conditions

Alzheimer’s disease (AD), a neurodegenerative disease, causes behavioural abnormalities such as disinhibition, impulsivity, and hyperphagia. Preclinical studies using AD model mice have investigated these phenotypes by measuring brain activity in awake, behaving mice. In this study, we monitored the...

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Detalles Bibliográficos
Autores principales: Sakurai, Keisuke, Shintani, Teppei, Jomura, Naohiro, Matsuda, Takeshi, Sumiyoshi, Akira, Hisatsune, Tatsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054396/
https://www.ncbi.nlm.nih.gov/pubmed/32127559
http://dx.doi.org/10.1038/s41598-020-60894-7