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Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy
BACKGROUND: Predictive preclinical models play an important role in the assessment of new treatment strategies and as avatar models for personalised medicine; however, reliable and timely model generation is challenging. We investigated the feasibility of establishing patient-derived xenograft (PDX)...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054410/ https://www.ncbi.nlm.nih.gov/pubmed/31919402 http://dx.doi.org/10.1038/s41416-019-0682-4 |