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Proteinuria is Associated with Urinary Loss of Cubilin and Vitamin D-Binding Protein in Patients with Preeclampsia

Women with preeclampsia (PE) form a vulnerable group for vitamin D3 deficiency. Reabsorption of vitamin D3 occurs in the proximal tubule after being endocytosed in combination with DBP (vitamin D binding protein) by the megalin/cubilin receptor. Because proteinuria promotes tubule injury and dysfunc...

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Detalles Bibliográficos
Autores principales: Albejante, Maria Clara, Kunz, Tânia Cristina Macedo, Ferreira, Matheus Feliciano Costa, Júnior, José Humberto Zago Ribeiro, de Almeida, Robson José, Bacigalupo, Lucas dos Santos, Matheus, Luiz Henrique Gomes, Dalboni, Maria Aparecida, Camacho, Cleber Pinto, Dellê, Humberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054416/
https://www.ncbi.nlm.nih.gov/pubmed/32127613
http://dx.doi.org/10.1038/s41598-020-60924-4