Ursodeoxycholic acid enriches intestinal bile salt hydrolase-expressing Bacteroidetes in cholestatic pregnancy

Ursodeoxycholic acid (UDCA) treatment can reduce itch and lower endogenous serum bile acids in intrahepatic cholestasis of pregnancy (ICP). We sought to determine how it could influence the gut environment in ICP to alter enterohepatic signalling. The gut microbiota and bile acid content were determ...

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Detalles Bibliográficos
Autores principales: Ovadia, Caroline, Perdones-Montero, Alvaro, Fan, Hei Man, Mullish, Benjamin H., McDonald, Julie A. K., Papacleovoulou, Georgia, Wahlström, Annika, Ståhlman, Marcus, Tsakmaki, Anastasia, Clarke, Louise C. D., Sklavounos, Alexandros, Dixon, Peter H., Bewick, Gavin A., Walters, Julian R. F., Marschall, Hanns-Ulrich, Marchesi, Julian R., Williamson, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054423/
https://www.ncbi.nlm.nih.gov/pubmed/32127609
http://dx.doi.org/10.1038/s41598-020-60821-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054423/
https://www.ncbi.nlm.nih.gov/pubmed/32127609
http://dx.doi.org/10.1038/s41598-020-60821-w

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