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Identification of a combination of transcription factors that synergistically increases endothelial cell barrier resistance

Endothelial cells (ECs) display remarkable plasticity during development before becoming quiescent and functionally mature. EC maturation is directed by several known transcription factors (TFs), but the specific set of TFs responsible for promoting high-resistance barriers, such as the blood-brain...

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Detalles Bibliográficos
Autores principales: Roudnicky, Filip, Kim, Bo Kyoung, Lan, Yanjun, Schmucki, Roland, Küppers, Verena, Christensen, Klaus, Graf, Martin, Patsch, Christoph, Burcin, Mark, Meyer, Claas Aiko, Westenskow, Peter D., Cowan, Chad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054428/
https://www.ncbi.nlm.nih.gov/pubmed/32127614
http://dx.doi.org/10.1038/s41598-020-60688-x