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YY1(lo) NKT cells are dedicated IL-10 producers

Co-expression of Yin Yang 1 (YY1) is required for the full function of the transcription factor, PLZF, which is essential for the development of natural killer T cell (NKT cell) effector functions. Discordant expression of YY1 and PLZF, therefore, might define NKT cell subsets with distinct effector...

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Detalles Bibliográficos
Autores principales: Darcy, Patrick W., Denzin, Lisa K., Sant’Angelo, Derek B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054430/
https://www.ncbi.nlm.nih.gov/pubmed/32127556
http://dx.doi.org/10.1038/s41598-020-60229-6