Cargando…

YY1(lo) NKT cells are dedicated IL-10 producers

Co-expression of Yin Yang 1 (YY1) is required for the full function of the transcription factor, PLZF, which is essential for the development of natural killer T cell (NKT cell) effector functions. Discordant expression of YY1 and PLZF, therefore, might define NKT cell subsets with distinct effector...

Descripción completa

Detalles Bibliográficos
Autores principales:	Darcy, Patrick W., Denzin, Lisa K., Sant’Angelo, Derek B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054430/ https://www.ncbi.nlm.nih.gov/pubmed/32127556 http://dx.doi.org/10.1038/s41598-020-60229-6

Ejemplares similares

Zbtb16 (PLZF) is stably suppressed and not inducible in non-innate T cells via T cell receptor-mediated signaling
por: Zhang, Sai, et al.
Publicado: (2015)

Histone deacetylase 3 is required for iNKT cell development
por: Thapa, Puspa, et al.
Publicado: (2017)

The transcriptional repressor NKAP is required for the development of iNKT cells
por: Thapa, Puspa, et al.
Publicado: (2013)

Abnormalities in iNKT cells are associated with impaired ability of monocytes to produce IL‐10 and suppress T‐cell proliferation in sarcoidosis
por: Crawshaw, Anjali, et al.
Publicado: (2014)

BATF regulates the development and function of IL-17 producing iNKT cells
por: Jordan-Williams, Kimberly L, et al.
Publicado: (2013)

Altered Development of NKT Cells, γδ T Cells, CD8 T Cells and NK Cells in a PLZF Deficient Patient
por: Eidson, Maggie, et al.
Publicado: (2011)

NKT cell status and IL-10-dependent therapeutic effect of NKT cell stimulation on collagen-arthritis in DBA/1 mice
por: Bessis, N, et al.
Publicado: (2005)

A SARS-CoV-2 Vaccine Designed for Manufacturability Results in Unexpected Potency and Non-Waning Humoral Response
por: Campbell, Elliot, et al.
Publicado: (2023)

Potential Role of IL-17-Producing iNKT Cells in Type 1 Diabetes
por: Li, Shamin, et al.
Publicado: (2014)

NKT10 cells: a novel iNKT cell subset
por: Wingender, Gerhard, et al.
Publicado: (2015)

Regulatory iNKT cells lack PLZF expression and control T(reg) cell and macrophage homeostasis in adipose tissue
por: Lynch, Lydia, et al.
Publicado: (2014)

Recollections of Charlie: Dr. Charles Alderson Janeway, Jr. (1943-2003)
por: Sant'Angelo, Derek B.
Publicado: (2003)

The Paf oncogene is essential for hematopoietic stem cell function and development
por: Amrani, Yacine M., et al.
Publicado: (2011)

The differentiation of ROR-γt expressing iNKT17 cells is orchestrated by Runx1
por: Thapa, Puspa, et al.
Publicado: (2017)

Integrative scATAC-seq and scRNA-seq analyses map thymic iNKT cell development and identify Cbfβ for its commitment
por: Wang, Jie, et al.
Publicado: (2023)

Natural Killer T (NKT) Cells and Periodontitis: Potential Regulatory Role of NKT10 Cells
por: Melgar-Rodríguez, Samanta, et al.
Publicado: (2021)

Improved Detection of Cytokines Produced by Invariant NKT Cells
por: Sag, Duygu, et al.
Publicado: (2017)

Identification of an IL-17–producing NK1.1(neg) iNKT cell population involved in airway neutrophilia
por: Michel, Marie-Laure, et al.
Publicado: (2007)

Invariant NKT cells modulate the suppressive activity of Serum Amyloid A-differentiated IL-10-secreting neutrophils
por: De Santo, Carmela, et al.
Publicado: (2010)

IL10 Secretion Endows Intestinal Human iNKT Cells with Regulatory Functions Towards Pathogenic T Lymphocytes
por: Burrello, Claudia, et al.
Publicado: (2022)

RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients
por: Venken, Koen, et al.
Publicado: (2019)

IL-13 Induces YY1 through the AKT Pathway in Lung Fibroblasts
por: Guo, Jia, et al.
Publicado: (2015)

TCR Affinity for Self-Ligands Influences the Development and Function of Encephalitogenic T Cells
por: Li, Jianwei, et al.
Publicado: (2011)

The IL-10 and IFN-γ pathways are essential to the potent immunosuppressive activity of cultured CD8(+ )NKT-like cells
por: Zhou, Li, et al.
Publicado: (2008)

Genome-wide analysis of YY2 versus YY1 target genes
por: Chen, Li, et al.
Publicado: (2010)

Antigen-specific human NKT cells from tuberculosis patients produce IL-21 to help B cells for the production of immunoglobulins
por: Wu, Changyou, et al.
Publicado: (2015)

Harnessing NKT cells for vaccination
por: Burn, Olivia K, et al.
Publicado: (2021)

β-Catenin is required for the differentiation of iNKT2 and iNKT17 cells that augment IL-25-dependent lung inflammation
por: Berga-Bolaños, Rosa, et al.
Publicado: (2015)

Retroposition and evolution of the DNA-binding motifs of YY1, YY2 and REX1
por: Kim, Jeong Do, et al.
Publicado: (2007)

Homeostasis Imbalance of YY2 and YY1 Promotes Tumor Growth by Manipulating Ferroptosis
por: Li, Yanjun, et al.
Publicado: (2022)

NKT Cells in Sepsis
por: Leung, Briana, et al.
Publicado: (2010)

Activation of iNKT Cells Prevents Salmonella-Enterocolitis and Salmonella-Induced Reactive Arthritis by Downregulating IL-17-Producing γδT Cells
por: Noto Llana, Mariángeles, et al.
Publicado: (2017)

IL-12 and IL-18 Induction and Subsequent NKT Activation Effects of the Japanese Botanical Medicine Juzentaihoto
por: Fujiki, Kazuhiko, et al.
Publicado: (2008)

The hot corona of YY Mensae
por: Güdel, M, et al.
Publicado: (1996)

The Natural Killer T (NKT) Cell Ligand α-Galactosylceramide Demonstrates Its Immunopotentiating Effect by Inducing Interleukin (IL)-12 Production by Dendritic Cells and IL-12 Receptor Expression on NKT Cells
por: Kitamura, Hidemitsu, et al.
Publicado: (1999)

The Timing and Abundance of IL-2Rβ (CD122) Expression Control Thymic iNKT Cell Generation and NKT1 Subset Differentiation
por: Won, Hee Yeun, et al.
Publicado: (2021)

Trained Immunity of IL-12-, IL-15-, and IL-18-Induced CD(3)+CD(56)+ NKT-Like Cells
por: Zhu, Siyu, et al.
Publicado: (2022)

YY males of the dioecious plant Mercurialis annua are fully viable but produce largely infertile pollen
por: Li, Xinji, et al.
Publicado: (2019)

NNKTT120, an anti-iNKT cell monoclonal antibody, produces rapid and sustained iNKT cell depletion in adults with sickle cell disease
por: Field, Joshua J., et al.
Publicado: (2017)

A Novel TCR Transgenic Model Reveals That Negative Selection Involves an Immediate, Bim-Dependent Pathway and a Delayed, Bim-Independent Pathway
por: Kovalovsky, Damian, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_9ujqldfitn5pieki9k6jmn5t4j