Isoforms of Cathepsin B1 in Neurotropic Schistosomula of Trichobilharzia regenti Differ in Substrate Preferences and a Highly Expressed Catalytically Inactive Paralog Binds Cystatin

Schistosomula (the post-infective stages) of the neurotropic schistosome Trichobilharzia regenti possess multiple isoforms of cathepsin B1 peptidase (TrCB1.1-TrCB1.6) with involvement in nutrient digestion. The comparison of substrate preferences of TrCB1.1 and TrCB1.4 showed that TrCB1.4 had a very...

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Detalles Bibliográficos
Autores principales: Dvořáková, Hana, Leontovyč, Roman, Macháček, Tomáš, O'Donoghue, Anthony J., Šedo, Ondřej, Zdráhal, Zbyněk, Craik, Charles S., Caffrey, Conor R., Horák, Petr, Mikeš, Libor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054455/
https://www.ncbi.nlm.nih.gov/pubmed/32175287
http://dx.doi.org/10.3389/fcimb.2020.00066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054455/
https://www.ncbi.nlm.nih.gov/pubmed/32175287
http://dx.doi.org/10.3389/fcimb.2020.00066

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