CK2 Inhibition Prior to Status Epilepticus Persistently Enhances K(Ca)2 Function in CA1 Which Slows Down Disease Progression

PURPOSE: Epilepsy therapy is currently based on anti-seizure drugs that do not modify the course of the disease, i.e., they are not anti-epileptogenic in nature. Previously, we observed that in vivo casein kinase 2 (CK2) inhibition with 4,5,6,7-tetrabromotriazole (TBB) had anti-epileptogenic effects...

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Detalles Bibliográficos
Autores principales: Schulze, Felix, Müller, Steffen, Guli, Xiati, Schumann, Lukas, Brehme, Hannes, Riffert, Till, Rohde, Marco, Goerss, Doreen, Rackow, Simone, Einsle, Anne, Kirschstein, Timo, Köhling, Rüdiger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054465/
https://www.ncbi.nlm.nih.gov/pubmed/32174814
http://dx.doi.org/10.3389/fncel.2020.00033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054465/
https://www.ncbi.nlm.nih.gov/pubmed/32174814
http://dx.doi.org/10.3389/fncel.2020.00033

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