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A conserved ATG2‐GABARAP family interaction is critical for phagophore formation

The intracellular trafficking pathway, macroautophagy, is a recycling and disposal service that can be upregulated during periods of stress to maintain cellular homeostasis. An essential phase is the elongation and closure of the phagophore to seal and isolate unwanted cargo prior to lysosomal degra...

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Detalles Bibliográficos
Autores principales: Bozic, Mihaela, van den Bekerom, Luuk, Milne, Beth A, Goodman, Nicola, Roberston, Lisa, Prescott, Alan R, Macartney, Thomas J, Dawe, Nina, McEwan, David G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054675/
https://www.ncbi.nlm.nih.gov/pubmed/32009292
http://dx.doi.org/10.15252/embr.201948412