Cargando…
A conserved ATG2‐GABARAP family interaction is critical for phagophore formation
The intracellular trafficking pathway, macroautophagy, is a recycling and disposal service that can be upregulated during periods of stress to maintain cellular homeostasis. An essential phase is the elongation and closure of the phagophore to seal and isolate unwanted cargo prior to lysosomal degra...
Autores principales: | Bozic, Mihaela, van den Bekerom, Luuk, Milne, Beth A, Goodman, Nicola, Roberston, Lisa, Prescott, Alan R, Macartney, Thomas J, Dawe, Nina, McEwan, David G |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054675/ https://www.ncbi.nlm.nih.gov/pubmed/32009292 http://dx.doi.org/10.15252/embr.201948412 |
Ejemplares similares
-
Atg9 establishes Atg2-dependent contact sites between the endoplasmic reticulum and phagophores
por: Gómez-Sánchez, Rubén, et al.
Publicado: (2018) -
The dynamic Atg13-free conformation of the Atg1 EAT domain is required for phagophore expansion
por: Lin, Mary G., et al.
Publicado: (2018) -
Peroxisomal Atg37 binds Atg30 or palmitoyl-CoA to regulate phagophore formation during pexophagy
por: Nazarko, Taras Y., et al.
Publicado: (2014) -
TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion
por: Tang, Zhenyuan, et al.
Publicado: (2019) -
No ATG8s, no problem? How LC3/GABARAP proteins contribute to autophagy
por: Martens, Sascha
Publicado: (2016)