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Interleukin‐12/23 deficiency differentially affects pathology in male and female Alzheimer's disease‐like mice

Pathological aggregation of amyloid‐β (Aβ) is a main hallmark of Alzheimer's disease (AD). Recent genetic association studies have linked innate immune system actions to AD development, and current evidence suggests profound gender differences in AD pathogenesis. Here, we characterise gender‐sp...

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Detalles Bibliográficos
Autores principales: Eede, Pascale, Obst, Juliane, Benke, Eileen, Yvon‐Durocher, Genevieve, Richard, Bernhard C, Gimber, Niclas, Schmoranzer, Jan, Böddrich, Annett, Wanker, Erich E, Prokop, Stefan, Heppner, Frank L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054677/
https://www.ncbi.nlm.nih.gov/pubmed/32003148
http://dx.doi.org/10.15252/embr.201948530