Cargando…
IGF1R regulates retrograde axonal transport of signalling endosomes in motor neurons
Signalling endosomes are essential for trafficking of activated ligand–receptor complexes and their distal signalling, ultimately leading to neuronal survival. Although deficits in signalling endosome transport have been linked to neurodegeneration, our understanding of the mechanisms controlling th...
Autores principales: | Fellows, Alexander D, Rhymes, Elena R, Gibbs, Katherine L, Greensmith, Linda, Schiavo, Giampietro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054680/ https://www.ncbi.nlm.nih.gov/pubmed/32030864 http://dx.doi.org/10.15252/embr.201949129 |
Ejemplares similares
-
Inhibiting p38 MAPK alpha rescues axonal retrograde transport defects in a mouse model of ALS
por: Gibbs, Katherine L., et al.
Publicado: (2018) -
In vivo imaging of axonal transport in murine motor and sensory neurons
por: Gibbs, Katherine L., et al.
Publicado: (2016) -
Bimodal regulation of axonal transport by the GDNF-RET signalling axis in healthy and diseased motor neurons
por: Rhymes, Elena R., et al.
Publicado: (2022) -
Botulinum Neurotoxins A and E Undergo Retrograde Axonal Transport in Primary Motor Neurons
por: Restani, Laura, et al.
Publicado: (2012) -
Retrograde transport of Akt by a neuronal Rab5-APPL1 endosome
por: Goto-Silva, Livia, et al.
Publicado: (2019)