Muscle‐derived GDF15 drives diurnal anorexia and systemic metabolic remodeling during mitochondrial stress

Mitochondrial dysfunction promotes metabolic stress responses in a cell‐autonomous as well as organismal manner. The wasting hormone growth differentiation factor 15 (GDF15) is recognized as a biomarker of mitochondrial disorders, but its pathophysiological function remains elusive. To test the hypo...

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Detalles Bibliográficos
Autores principales: Ost, Mario, Igual Gil, Carla, Coleman, Verena, Keipert, Susanne, Efstathiou, Sotirios, Vidic, Veronika, Weyers, Miriam, Klaus, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054681/
https://www.ncbi.nlm.nih.gov/pubmed/32026535
http://dx.doi.org/10.15252/embr.201948804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054681/
https://www.ncbi.nlm.nih.gov/pubmed/32026535
http://dx.doi.org/10.15252/embr.201948804

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